Specifically, the live-action movie begins almost exactly like the anime, complete with Saya taking out a salaryman in a '70s subway car and the shadowy government agent who are perturbed that the salaryman in question didn't turn into a vampire. It's also the same in that whoever they hired to be the American agents are terrible actors.

The only real change that I can tell, besides the silly opening summary, is that the vampires are called "bloodsuckers," which is exceedingly goofy, especially as delivered by these "actors." Still, you can do far worse that copy the Blood anime scene for scene, so even though it's in preposterously lo-res, I'll give it the benefit of the doubt.