4) Girls' Soccer Team
3) Numbers Station Transmissions
As Ajira 316, guided by kick-ass pilot Frank "We're not going to Guam, are we?" Lapidus, approached the Island for a rough landing, the Numbers mysteriously called out through the radio. The freaky part about this was that Island nutjob Danielle Rousseau had shut down the Numbers transmission that had been broadcasting from a radio tower on the Island sometime in the '80s and replaced it with a distress call. So who turned the Numbers back on during the time the Oceanic Six were away from the Island? Was the transmission coming from the past? It's a startling mystery, and one that's easy to miss over the chaos of the panicked landing.
To add even more intrigue, actor Jorge Garcia (Hurley) admitted that in the previous episode, it was his voice reciting the Numbers that Danielle's science team originally followed to the Island (although it didn't sound like him in the transmission later picked up by Ajira 316). It makes you think that the writers might have originally envisioned a paradoxical plotline in which time-traveling Hurley (during his Dharma days) recorded the very Numbers that a fellow mental patient later heard and repeated to Hurley, who played them in the lotto and was led by them to the Island in the first place. But it never happened on-screen and we'll probably never know.
2) "Make Your Own Kind of Music"
Unlucky Desmond got saddled with Hatch duty, in which his life was guided and surrounded by the Numbers. Every 108 minutes (the sum of the Numbers), he had to enter the Numbers into the Swan station computer to prevent the Earth from being destroyed. (God knows how he got any restorative sleep.) He had to inject himself daily with a vaccine that was labeled with the Numbers and was protecting hjm from a possibly bogus Island Sickness. At least Desmond got to enjoy spinning some vinyl, blasting "Make Your Own Kind of Music" by Mama Cass as he went through his morning routine. That's how we met him and first saw what was down the Hatch in the fantastic opening to Season 2. However, Desmond's morning groove began 42 seconds into the scene and was cut short at exactly 1:08 into the song by Jack and Locke dynamiting the Hatch. Damn Numbers! There is no escape! Brilliant editing, all around.
1) Flight 815
The crash of Oceanic 815 is the crux of the Lost mythos, and it is fittingly surrounded by the Numbers. Just to name a few instances: The fact that it's Flight 815. There were 324 passengers and crew on the flight (108x3). Jack, Rose and Bernard sat in Row 23, while Ana Lucia sat in Row 42. The Oceanic Six were rescued 108 days after the crash. The only members of the flight who survived their Island adventures despite being in the cross-hairs as Jacob's Candidates were Hurley and Sawyer, #8 and #15, respectively. Just more proof that the Numbers were harbingers of destiny.